mi 2 — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T28036	MI-2-2	MI22,MI 2 2	Histone Methyltransferase
	MI-2-2 is an inhibitor of bivalent protein-protein interaction between menin and MLL with an IC50 of 46 nM. MI-2-2 binds to menin with Kd of 22 nM.		Histone Methyltransferase
T2350	MALT1 inhibitor MI-2	MALT1 inhibitor,MI 2,MI 2 (MALT1 inhibitor)	MALT
	MI-2 (MALT1 inhibitor) is an irreversible MALT1 inhibitor.		MALT
T2649	Menin-MLL inhibitor MI-2	Menin-MLL Inhibitor,MI2,MI-2,Menin-MLL inhibitor 2,MI 2	Apoptosis , Epigenetic Reader Domain , Histone Methyltransferase
	Menin-MLL inhibitor MI-2 (MI2) is a potent menin-MLL interaction inhibitor with IC50 of 446 nM.
T22978	MI-2 (hydrochloride)		Others
	MI-2 (Menin-MLL Inhibitor) is an effective menin-MLL interaction inhibitor (IC50: 446 ± 28 nM).		Others
T6585	SAR405838	MI773,MI 773,MI-77301,MI-773	Mdm2 , E1/E2/E3 Enzyme
	MI-773 (SAR405838 (MI 773)) is an orally available MDM2 antagonist with Ki of 0.88 nM. Phase 1.		Mdm2 , E1/E2/E3 Enzyme
T28029	Methylisothiazolinone hydrochloride	N-Methylisothiazolin-3-one,MI,KB-838,Methylisothiazolinone HCl
	Methylisothiazolinone is a powerful synthetic biocide and preservative.
T13748	L-2-Hydroxyglutaric acid disodium	(S)-2-Hydroxyglutaric acid disodium	Histone Demethylase , Mitochondrial Metabolism
	L-2-Hydroxyglutaric acid disodium ((S)-2-Hydroxyglutaric acid disodium) is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activ...		Histone Demethylase , Mitochondrial Metabolism
T69640	MI-1851
	MI-1851 is a potent peptidomimetic inhibitor. MI-1851could prevent proteolytic processing of the S protein from SARSCoV-2 by endogenous furin in HEK293 cells.
T69540	MI-30
	MI-30 is a SARS-CoV-2 Protease inhibitor (IC50 = 17.2 nM). In a transgenic mouse model of SARS-CoV-2 infection, oral or intraperitoneal treatment, MI-30 significantly reduced lung viral loads and lung lesions.
T68394	MI-219
	MI-219 is a human double minute 2 (HDM2) inhibitor.
T69541	MI-23
	MI-23 is a SARS-CoV-2 Protease inhibitor (IC50 = 7.6 nM).
T69524	MI-09
	MI-09 is a SARS-CoV-2 Protease inhibitor (IC50 = 15.2 nM). In a transgenic mouse model of SARS-CoV-2 infection, oral or intraperitoneal treatment with MI-09 significantly reduced lung viral loads and lung lesions.
T21898	MI-192
	MI-192 is a selective HDAC2 and HDAC3 inhibitor with IC 50 s of 30 nM and 16 nM, respectively. MI-192 is more selective for HDAC2/3 than other HDAC isomers.MI-192 induces myeloid leukaemic cells apoptosis. MI-192 has pot...
T71223	SR-33805
	SR-33805 is a calcium channel antagonist potentially for the treatment of atherosclerosis and heart failure. SR-33805 restored the MI-altered cell shortening without affecting the Ca(2+) transient amplitude, suggesting ...
T13749	L-2-Hydroxyglutaric acid	(S)-2-Hydroxyglutaric acid	Others
	L-2-Hydroxyglutaric acid, an epigenetic modifier and potential oncometabolite in renal cancer, impedes mitochondrial creatine kinase (Mi-CK) activity, exhibiting Km and Ki values of 2.52 mM and 11.13 mM, respectively. Ad...		Others
T74247	TPE-MI
	Tetraphenylethene maleimide (TPE-MI) serves as a thiol probe to assess unfolded protein levels and proteostasis within cells. It is particularly effective in identifying proteostasis imbalances in both induced pluripoten...
T78887	ROS-IN-2		Reactive Oxygen Species
	ROS-IN-2 (compound 85), a seco-lupane triterpenoid derivative, inhibits reactive oxygen species (ROS) production and shields mitochondria from oxidative damage by curtailing the generation of oxidative stressors. It has ...		Reactive Oxygen Species
T73661	Delcasertib hydrochloride
	Delcasertib (KAI-9803) hydrochloride, a potent and selective δ-protein kinase C (δPKC) inhibitor, shows promise in reducing ischemia and reperfusion injury in animal models of acute myocardial infarction (MI) [1] [2].
T37963	Methylchloroisothiazolinone/Methylisothiazolinone Mixture
	Methylchloroisothiazolinone/methylisothiazolinone mixture (MCIT/MIT) is a mixture of isothiazolinone-derived biocides.1,2It is effective against Gram-positive and Gram-negative bacteria with MIC values of 0.0002, 0.0002,...